About Pain

Pain is a universal experience for most of us, although, some people are born with rare conditions in which they cannot perceive it, called CIP. There are two established categories of pain that can be very broad in scope.

 

Nociceptive and Neuropathic Pain

Nociceptive pain, or pain that arises from tissue damage, is well known to anyone who has broken a bone, been stung by a bee, or burned his or her skin. Neuropathic pain is caused by damage to the nervous system.

 

Conditions that produce pain can belong to both types, but can usually be well classified into one of the two categories. Some conditions, such as fibromyalgia, can be more difficult to classify, as they are probably a pain system dysfunction.

 

Whatever the case may be, physical pain is affecting people worldwide every day.  When pain is severe, it hinders the most basic tasks of daily life.

 

What Causes Pain

A prevalent quality of pain is that it compels to be explained. Here a few causes of pain:

  •      Chronic low-grade inflammation
  •      Muscle tension and contracture
  •      Vitamin D deficiency
  •      Pathological sensitization
  •      Injury
  •      Sensitization
  •      Muscle Knots

 

Whether perceiving pain physically or mentally the experience of pain is very real. Due to it being triggered by various factors and affecting individuals differently, pain is treated with a variety of medications and/or therapies.

 

Normal Treatments for Pain Management

Most pain is treated by physical therapy and prescription drugs or over-the-counter medications. The most prevalent of these types of treatment is prescribing [semisynthetic opioid-based drugs] like:

 

·   Fentanyl

·   Hydrocodone

·   Methadone

·   Morphine

·   Oxycodone

·   Oxymorphone

·   Codeine

·   Hydromorphone

 

Brand names for pain management medication include Vicodin, Lortab, Roxanol, Oxycontin, Percocet, etc.

 

Originally, opioids were only given to terminally ill patients or for acute short-term pain, like recovery from surgery. However, in the 1990’s came the rise of giant pharmaceutical companies and with it an opioid abuse epidemic of a massive proportion.

 

It’s estimated that 60 people die every day in the US due to prescription opioid-related problems. According to the American Society of Addiction and Medicine, in 2015, 2 million people had a substance abuse disorder involving prescription pain relievers. Subsequently, over half a million more had a disorder with heroin involved.

 

According to the CDC’s latest reports, in the last 16 years, more than 183,000 Americans have died from overdoses related to prescription opioids. People who take painkillers regularly can quickly develop a tolerance and dependence. Evidence shows prescription opioid addiction often leads to heroin addiction. A deadly prescription addiction, opioids are being overprescribed.

 

Medical Marijuana and Current Treatments

Medical Marijuana vs. Prescription Opioids

A review of 28 studies led by Harvard University examined the efficacy of [cannabinoids] in treating a variety of pain and medical issues. The studies showed [cannabis] to significantly improve symptoms of chronic and neuropathic pain. A study published in The Journal of Pain presents data finding that cannabis not only increased the quality of life and decreased the side effects from other medications in patients, but it also reduced the use of opioids on average by 64%.

 

How Medical Marijuana Helps Manage Pain

Humans and most animals have [endogenous cannabinoid receptors] found throughout the brain and the nervous system.  These receptors and the [neuromodulatory lipids] that bind with them are called the [endocannabinoid system]. Cannabinoids work within this system to help modulate [nociception] and opioid production.

 

Marijuana contains [phytocannabinoids] like [THC] and [CBD]. When marijuana is consumed, THC and CBD bind to the CB-1 and CB-2 endocannabinoid receptors, acting in place of their endogenous analogs.

 

Medical marijuana, simply put, supplements the body’s natural pain management system helping to relieve symptoms of acute and chronic pain.

 

Using Medical Marijuana to Manage Pain

Individuals respond uniquely to cannabis depending on a variety of factors including genetics, dosage, strain, tolerance, and the method in which it is administered. When beginning to treat pain with cannabis, it’s advised to start with low doses and increase as needed.

 

Patients seeking relief from symptoms associated with pain seem to find the best results with [Indica] dominant strains. When THC and CBD are adequately balanced in [hybrid strains], the body experiences [“the entourage effect”], wherein the multiple cannabinoids work together synergistically providing medicinal relief.

 

One chronic pain study concluded that a single inhalation of 25 mg of 9.4% THC cannabis three times daily for five days reduced the intensity of pain, improved sleep, and was well tolerated. Cannabis will affect each person differently. Consult with a physician and medical marijuana professional about using cannabis and find links below to strains have been associated with relief from acute and chronic symptoms of pain.

 

·   [[Afgooey]]

·   [[Afwreck]]

·   [[Alien Dawg]]

·   [[Alien Kush]]

·   [[Alien OG]]

·   [[Ambrosia]]

·   [[Animal Cookies]]

·   [[Avalon]]

·   [[Berry Bomb]]

·   [[Black Cherry Soda]]

·   [[Black Domina]]

·   [[Black Mamba]]

·   [[Blue Crack]]

·   [[Blue Dragon]]

·   [[Blue God]]

·   [[Blue Goo]]

·   [[Blue OG]]

·   [[Blueberry Headband]]

·   [[Bruce Banner]]

·   [[Bubba Kush]]

 

Sources:

http://www.nsc.org/learn/NSC-Initiatives/Pages/prescription-drug-abuse.aspx

http://www.sciencedirect.com/science/article/pii/S1526590016005678

https://www.asam.org/docs/default-source/advocacy/opioid-addiction-disease-facts-figures.pdf

https://www.cdc.gov/drugoverdose/data/prescribing.html

https://www.ncbi.nlm.nih.gov/pubmed/26103031

http://www.cmaj.ca/content/182/14/E694.short

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